条件性疼痛调节的影响因素与慢性疼痛

摘要

作为评价内源性镇痛强度的新方法,条件性疼痛调节(CPM)受损意味着机体痛觉下行抑制作用减弱,发生慢性疼痛的概率增加,而年龄、心理因素和体育锻炼等均能对个体CPM产生影响.同时,采取统一标准的CPM检测方法对不同研究间进行比较有重要意义.%As a new laboratory test for evaluation of endogenous pain inhibition,conditioned pain modulation (CPM) deficiency means dysfunction of endogenous pain inhibitory systems and higher incidence of chronic pain.Age,psychological factors and physical activity all seem to influence the individual CPM effect.A standard CPM testing way has an important role in comparison between different researches.