Plasmid mediated multiple antibiotic resistance in Escherichia coli isolated from community acquired infection of urinary tract in Aligarh Hospital

摘要

This study was to investigate the current trends of multiple drug resistance in bacteria against antibiotics for the proper empirical treatmen.Clinical isolates were collected from community-acquired infection of urinary tract patients in Aligarh India from March 1999 to August 1999.Antibiotic susceptibility test was performed,using the disc diffusion method followed by plasmid isolation by the method of Kado and Liu.Transfer experiments were performed by the method of Lederberg and Cohen.Clinical study revealed that this infection was more common in young women.Various strains of E.coli isolated during the course of study were found to show multiple antibiotic resistance which was further characterized as plasmid-borne drug resistance.This study shows that E.coli may be one of the important causative agents of urinary tract infection (UTI )in young women.