Recently the His-Purkinje system has been found to play an important role in the genesis of ventricular arrhythmias. The anatomic and cellular electrophysiologic complexity of the left ventricular conduction system appears to favor reentrant ventricular tachycardia in both diseased and healthy hearts. Newer discoveries strongly suggest the Purkinje system as the cause of ventricular arrhythmias in patients with short-coupled premature ventricular complexes and in those with catecholaminergic polymorphous ventricular tachycardia. With understanding of mechanisms related to His-Purkinje system and ventricular arrhythmias, many cardiac arrhythmias appears to involve the ventricular specialized conduction system and may be treated with catheter ablation.%近期研究提示希氏-浦肯野系统与室性心律失常的发生关系密切.作为左室的特殊传导组织,希氏-浦肯野系统的解剖与电生理特点,使其在正常或病理情况下易于参与折返型心律失常形成.目前资料提示浦肯野系统病变是短联律间期室性早搏相关心律失常和儿茶酚胺敏感性多形性室性心动过速的原因.随着对希氏-浦肯野系统与室性心律失常关系的认识,导管消融可作为此类心律失常的治疗途径.
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