The protective effect of G. Lucidum and P. Cocos extractive formula on chemical liver injury was studied by a CCl4-injuried liver model. The results showed that compared with the control group the mice treated at a dose of 1.2 g/kg BW per day for 30 days were significantly decreased in the activities of serum glutamic-pyruvic transaminase(SGPT)and serum glutamic-oxaloacetic transaminase (SGOT)and the rates of liver cell necrosis and lesions,and their body weight gain was not adversely affected by the extractive formula.%采用四氯化碳引起的肝损伤动物模型,对灵芝茯苓提取物组方的保肝作用进行了研究.结果表明:与模型对照组(0g/kg BW)比较,1.2 g/kg BW剂量组的小鼠血清谷丙转氨酶活力、血清谷草转氨酶活力、肝细胞坏死平均分和肝细胞病变各种类型总平均分均显著降低,受试物对小鼠体重增长无不良影响.
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