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Physicochemical modulation of huntingtin aggregation on lipid membranes: Implications for Huntington's disease

机译：脂膜对亨廷汀聚集的物理化学调节：亨廷顿疾病的影响

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作者
Chaibva, Maxmore.;
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作者单位

West Virginia University.;

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授予单位 West Virginia University.;
学科
学位 Ph.D.
年度 2016
页码 177 p.
总页数 177
原文格式 PDF
正文语种 eng
中图分类
关键词
Atomic force microscopy; Curved lipid bilayers; Huntingtin acetylation; Huntingtin exon1; Huntington's disease; Protein aggregation;

机译：原子力显微镜;弯曲的脂质双层;亨廷顿乙酰化;亨廷顿外国人1;亨廷顿氏病;蛋白质聚集;

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专利

1. Chapter 9 The Disease Protein Huntingtin and Neuronal Protein Aggregations in Huntington's Disease (HD) [J] . Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Advances in anatomy embryology and cell biology. . 2015,第Null期

机译：第9章亨廷顿舞蹈病（HD）中的疾病蛋白Huntingtin和神经元蛋白聚集
2. Effects of ginseng and ginsenosides on mutant huntingtin aggregation, cellular apoptosis, mitochondrial dysfunction and motor impairment of Huntington's disease model [J] . European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology . 2019,第S6期

机译：人参和人参苷对亨廷顿疾病模型突变亨廷特素聚集，细胞凋亡，线粒体功能障碍及电机损伤的影响
3. Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAG _n51trunc Model of Huntington Disease [J] . Anne-Christine Plank, Fabio Canneva, Kerstin A. Raber, Frontiers in Neuroscience . 2018,第2016期

机译：亨廷顿病经典CAG _{n51trunc 模型的同系F344大鼠品系中操作性能的早期改变和Huntingtin聚集}
4. An Integrative Proteomic Approach to Identify Huntingtin Protein Networks Using a Novel BAC Transgenic Model of Huntington's Disease [C] . Dyna Shirasaki, Erin R. Greiner, Pinmanee Boontheung, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：一种综合的蛋白质组学方法，用于使用亨廷顿氏病的新型BAC转基因模型鉴定亨廷蛋白网络
5. Therapeutic implications of mutant huntingtin-induced dysregulation of brain iron homeostasis in a mouse model of Huntington's disease. [D] . Marks, Eileen S. 2011

机译：亨廷顿氏病小鼠模型中突变亨廷顿蛋白诱导的脑铁稳态失调的治疗意义。
6. TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntingtons disease models [O] . Ramanath Narayana Hegde, Anass Chiki, Lara Petricca, 2020

机译：TBK1磷酸化突变体亨廷顿并抑制了亨廷顿疾病模型的聚集和毒性
7. Acetylation Regulates the Interaction of Huntingtin with Lipid Membranes: Implications for Huntington Disease [O] . Chaibva Maxmore, Arndt James R., Valentine Stephen J., 2015

机译：乙酰化调节亨廷顿蛋白与脂膜的相互作用：对亨廷顿病的影响

Physicochemical modulation of huntingtin aggregation on lipid membranes: Implications for Huntington's disease

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