The impact of dosimetric optimization using respiratory gating and inhomogeneity corrections on potential therapeutic gain in patients with lung cancer.

摘要

Early stage lung cancer is found with increasing frequency by screening high risk patients. Recently, the use of Stereotactic Body Radiation Therapy (SBRT) has been found to be highly successful. The hypothesis being tested here is that the use of respiratory gating and tissue heterogeneity corrections are necessary to optimize tumor and normal tissue dose distributions for SBRT.