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Elucidating the Abilities of MDM2, MDMX and p21 to Regulate Ferroptosis

机译：阐明MDM2，MDMX和P21的能力调节裂解症

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作者
Venkatesh, Divya.;
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作者单位

Columbia University.;

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授予单位 Columbia University.;
学科
学位 Ph.D.
年度 2020
页码 186 p.
总页数 186
原文格式 PDF
正文语种 eng
中图分类 AAI28088753;
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专利

1. MDMX Promotes Proteasomal Turnover of p21 at G1 and Early S Phases Independently of, but in Cooperation with, MDM2 [J] . Yetao Jin, Shelya X. Zeng, Xiao-Xin Sun, Molecular and Cellular Biology . 2008,第4期

机译：MDMX独立于MDM2，但与MDM2合作促进G1和S期早期的p21蛋白酶体转化
2. A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize [J] . Pavlína Kosztyu, Iva Slaninová, Barbora Val?íková, Frontiers in Physiology . 2019,第10期

机译：一个保守的氨基酸残基作为Mdm2和MdmX RING域二聚能力差异的关键上下文特定决定因素
3. Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway [J] . Fan Yangwei, Li Mengya, Ma Ke, Cancer biology & therapy . 2019,第4a6期

机译：双靶MDM2 / MDMX抑制剂增加了多柔比星的敏化，并通过激活Tab1 / Tak1 / P38 Mapk路径来抑制三阴性乳腺癌细胞的迁移和侵袭能力
4. Peptide-Guided Design of Mdm2/MdmX Inhibitors with Anticancer Activity [C] . Lingyun Qin, Yao Chen, Rong Chen American Peptide Symposium . 2015

机译：抗癌活动MDM2 / MDMX抑制剂的肽导向设计
5. Context Dependent Roles of MDMX (MDM4) and MDM2 in Breast Cancer Proliferation and Circulating Tumor Cells [D] . Gao, Chong 2019

机译：MDMX（MDM4）和MDM2在乳腺癌增殖和循环肿瘤细胞中的上下文相关作用
6. MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling [O] . Divya Venkatesh, Nicholas A. OBrien, Fereshteh Zandkarimi, 2020

机译：MDM2和MDMX通过PPARα介导的脂质重塑促进裂解菌
7. MDMX Promotes Proteasomal Turnover of p21 at G1 and Early S Phases Independently of, but in Cooperation with, MDM2▿ † [O] . Jin, Yetao, Zeng, Shelya X., Sun, Xiao-Xin, 2007

机译：MDMX独立于MDM2，但与MDM2合作促进G1和S期早期的p21蛋白酶体转化

Elucidating the Abilities of MDM2, MDMX and p21 to Regulate Ferroptosis

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