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Antigen Stability Influences Processing Efficiency Immunogenicity of Pseudomonas Exotoxin Domain III and Ovalbumin

机译：抗原稳定性影响Pseudomonas外毒素结构域III和卵巢的处理效率免疫原性

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作者
Moss, Daniel Laurence.;
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作者单位

Tulane University Graduate Program in Biomedical Sciences.;

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授予单位 Tulane University Graduate Program in Biomedical Sciences.;
学科
学位 Ph.D.
年度 2020
页码 168 p.
总页数 168
原文格式 PDF
正文语种 eng
中图分类 AAI27958252;
关键词
Antigen processing; CD4+ T cells; Exotoxin A; Immunogenicity;

机译：抗原加工;CD4 + T细胞;Exotoxin a;免疫原性;

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专利

1. Elimination of factor VIII VIII ‐specific B cells by immunotoxins composed of a single factor VIII VIII domain fused to Pseudomonas Pseudomonas exotoxin A [J] . Brettschneider K., Schmidt A., Kahle J., Journal of thrombosis and haemostasis: JTH . 2018,第11期

机译：通过免疫毒素的消除因子VIII VIII-特异性B细胞组成的单因素VIII VIII结构域，融合给假单胞菌副毒素Audodomonas exotoxin a
2. THE CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA EXOTOXIN DOMAIN III WITH NICOTINAMIDE AND AMP - CONFORMATIONAL DIFFERENCES WITH THE INTACT EXOTOXIN [J] . Li M., Benhar I., Pastan I., Proceedings of the National Academy of Sciences of the United States of America . 1995,第20期

机译：烟酰胺铜绿假单胞菌外毒素区域III的晶体结构和完整的外毒素的AMP构象差异。
3. Elimination of FVIII-Specific B Cells By Immunotoxins Comprised of a Single FVIII Domain Fused to Pseudomonas Exotoxin a [J] . Brettschneider Kerstin, Schmidt Anja, Kahle Joerg, Blood: The Journal of the American Society of Hematology . 2016,第22期

机译：通过融合到假单胞菌外毒素a的单个FVIII结构域的免疫毒素消除FVIII特异性B细胞
4. Conjugation of ovalbumin to trimethyl chitosan improves immunogenicity of the antigen [C] . Bram Slutter, Peter Soema, Zhi Ding, Annual meeting exposition of the Controlled Release Society . 2011

机译：卵清蛋白与三甲基壳聚糖的缀合可改善抗原的免疫原性
5. The kinetic stability of class II: Peptide complexes controls immunogenicity via the efficiency of antigen presentation. [D] . Lazarski, Christopher Andrew. 2006

机译：II类：肽复合物的动力学稳定性通过抗原呈递的效率控制免疫原性。
6. Deimmunizing substitutions in Pseudomonas exotoxin domain III perturb antigen processing without eliminating T-cell epitopes [O] . Daniel L. Moss, Hee-Won Park, Ramgopal R. Mettu, 2019

机译：在不消除T细胞表位的情况下假单胞菌外毒素域III的去免疫取代扰动抗原加工
7. The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin. [O] . Li, M, Dyda, F, Benhar, I, 1995

机译：带有烟酰胺和AMP的铜绿假单胞菌外毒素结构域III的晶体结构：与完整外毒素的构象差异。
8. Mutational Effects on Protein Folding Stability and Antigenicity: The Case of Streptococcal Pyrogenic Exotoxin A [R] . Carra, J. H. , Welcher, B. C. , Schokman, R. D. , 2003

机译：蛋白质折叠稳定性和抗原性的突变效应：链球菌热原外毒素a的案例

Antigen Stability Influences Processing Efficiency Immunogenicity of Pseudomonas Exotoxin Domain III and Ovalbumin

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