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Functional and Single-cell Genomic Tools Identify Potential Novel Molecular Vulnerabilities in Breast and Gastrointestinal Cancers

机译：功能性和单细胞基因组工具识别乳腺和胃肠癌中的潜在新的分子脆弱性

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作者
Rao, Manisha .;
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作者单位

State University of New York at Stony Brook.;

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授予单位 State University of New York at Stony Brook.;
学科
学位 Ph.D.
年度 2020
页码 109 p.
总页数 109
原文格式 PDF
正文语种 eng
中图分类 AAI27737286;
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1. 三阴性乳腺癌患者因新辅助或辅助化疗引起的早发性心脏事件与其基因组DNA中某些新的自噬相关单核苷酸多态性的相关性研究:一项真实世界研究 [J] . Binliang Liu, Yuhui Zhang, Binghe Xu, 癌症（英文版） . 2019,第007期
2. Genomic and epigenomic analysis identify potential therapeutic targets in luminal B breast cancer molecular subtype [J] . Klouche L. Addou, Belhadj A., Bendaoud A., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2014,第Suppla6期

机译：基因组和表观基因组分析确定了管腔B型乳腺癌分子亚型的潜在治疗靶标
3. Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics [J] . Goran Jonsson, Johan Staaf, Johan Vallon-Christersson, Breast Cancer Research . 2010,第3期

机译：通过阵列比较基因组杂交鉴定的乳腺癌基因组亚型表现出独特的分子和临床特征
4. Modelling the tumour microenvironment and employing functional genomics identifies CREBBP as a novel tumour surpressor in triple negative breast cancers [J] . Peck Barrie, Maguire Sarah, Morrison Eamonn, Breast cancer research and treatment. . 2016,第1期

机译：对肿瘤微环境进行建模并采用功能基因组学可以确定CREBBP是三阴性乳腺癌中一种新型的肿瘤抑制因子
5. Breast Cancer Genomics: Tackling Complexity with Functional Genomics and Patient-Derived Organoids [C] . Ron Bose International Symposium on Mathematical and Computational Oncology . 2019

机译：乳腺癌基因组学：解决功能基因组学和患者衍生类生物的复杂性
6. Use of molecular genetics and functional genomics to: (i) Understand dichlorodiphenyltrichloroethane (DDT) resistance in Drosophila melanogaster and (ii) identify vulnerable target gene systems in Pediculus humanus humanus (body louse) and Callosobrucus maculatus (Cowepea weevil). [D] . Pedra, Joao Helbert Ferreira. 2004

机译：利用分子遗传学和功能基因组学来：（i）了解黑腹果蝇（Drosophila melanogaster）对二氯二苯基三氯乙烷（DDT）的抗性，以及（ii）在人类Pediculus humanus humanus（体虱）和Callosobrucus maculatus（Cowepea weevil）中识别易受攻击的靶基因系统。
7. Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer [O] . Yew Chung Tang, Szu-Chi Ho, Elisabeth Tan, 2018

机译：功能基因组学可识别PTEN缺陷型乳腺癌中的特定漏洞
8. Integration of genomic profiling and functional screening identifies potential driver somatic copy number alterations in triple-negative breast cancer [O] . G. Xie, X. Xu 2020

机译：基因组分析和功能筛选的整合鉴定了三阴性乳腺癌中的潜在驾驶员体细胞拷贝数改变
9. Functional Genomics Approach to Identify Novel Breast Cancer Gene Targets in Yeast [R] . Bennett, C. B. 2005

机译：功能基因组学方法识别酵母中的新型乳腺癌基因靶点

Functional and Single-cell Genomic Tools Identify Potential Novel Molecular Vulnerabilities in Breast and Gastrointestinal Cancers

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