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Development of a Selective and Stable Reactive Oxygen Species-activated Anti-Acute Myeloid Leukemia Agent and Localizing DNA Aptamer

机译：开发一种选择性和稳定的活性氧物质 - 活化的抗急性髓性白血病药剂和定位DNA适体

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作者
Earnest, Kaylin Grace.;
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作者单位

University of Cincinnati.;

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授予单位 University of Cincinnati.;
学科
学位 Ph.D.
年度 2018
页码 96 p.
总页数 96
原文格式 PDF
正文语种 eng
中图分类 AAI27602855;
关键词
Reactive oxygen species; Aptamer; Acute myeloid leukemia; Anticancer agents; Pro-drug strategy;

机译：反应性氧气;适体;急性髓性白血病;抗癌代理人;专业药物策略;
入库时间 2022-08-17 12:01:10

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专利

1. Reactive oxygen species-activated nanomaterials as theranostic agents [J] . Kim Kye S., Lee Dongwon, Song Chul Gyu, Nanomedicine . 2015,第17期

机译：活性氧激活纳米材料作为治疗剂
2. Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo [J] . Cao Zhi-Xing, Wen Yi, He Jun-Lin, Molecular pharmacology. . 2019,第5期

机译：来自甘草的口服的天然FLT3抑制剂Isoliquiritigenin，在体外和体内表现出选择性抗急性髓性白血病疗效
3. Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3-morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl} -3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo [J] . Li W.-W., Wang X.-Y., Zheng R.-L., Journal of Medicinal Chemistry . 2012,第8期

机译：新的有效和选择性FLT3抑制剂1- {5- [7-（3-吗啉代丙氧基）喹唑啉-4-基硫基]-[1,3,4]噻二唑-2-基} -3-p-甲苯基脲的发现及其体内外抗急性髓性白血病（AML）活性
4. Perturbation of the phosphoproteome of colony stimulating factor 3 receptor (CSF3R) in normal myeloid development, myeloid leukemia and neutrophilic leukemia [C] . Pankaj Dwivedi, David Muench, Mohammad Azam, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：正常髓样发育中菌落刺激因子3受体（CSF3R）的磷脂蛋白酶的扰动，髓性白血病和中性白血病
5. Loss of Egr1 plays a role in murine leukemogenesis and may play a role in the development of acute myeloid leukemia and therapy-related acute myeloid leukemia. [D] . Joslin, John M. 2006

机译：Egr1的丢失在小鼠白血病的发生中起作用，并且可能在急性髓细胞性白血病和与治疗有关的急性髓细胞性白血病的发展中起作用。
6. Reactive oxygen species-activated nanomaterials as theranostic agents [O] . Kye S Kim, Dongwon Lee, Chul Gyu Song, -1

机译：活性氧激活纳米材料作为治疗剂
7. Reactive oxygen species-activated nanomaterials as theranostic agents [O] . Kye S Kim, Dongwon Lee, Chul Gyu Song, 2015

机译：活性氧物质 - 活性纳米材料作为治疗剂

Development of a Selective and Stable Reactive Oxygen Species-activated Anti-Acute Myeloid Leukemia Agent and Localizing DNA Aptamer

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