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Defining the Dynamics Between the Gut Microbiota, Microbial Derived Secondary Bile Acid Ursodeoxycholic Acid (UDCA), and Clostridioides difficile Pathogenesis

机译：定义肠道菌群，微生物衍生的次级胆汁酸熊去氧胆酸（UDCA）和艰难梭菌发病机理之间的动力学

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作者
Winston, Jenessa Andrzejewski;
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作者单位

North Carolina State University;

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授予单位 North Carolina State University;
学科
学位 Ph.D.
年度 2019
页码 258 p.
总页数 258
原文格式 PDF
正文语种 eng
中图分类
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专利

1. Inhibition of spore germination, growth, and toxin activity of clinically relevant C-difficile strains by gut microbiota derived secondary bile acids [J] . Thanissery Rajani, Winston Jenessa A., Theriot Casey M. Anaerobe . 2017,第期

机译：通过肠道微生物衍生的二甲酸抑制孢子萌发，生长和临床相关的C-艰难菌株的毒素活性
2. Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract [J] . Winston Jenessa A., Theriot Casey M. Anaerobe . 2016,第Null期

机译：微生物衍生的胆汁酸对胃肠道中艰难梭菌定殖性的影响
3. Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine [J] . Casey M. Theriot, Alison A. Bowman, Vincent B. Young mSphere . 2016,第1期

机译：抗生素诱导的肠道菌群改变改变次级胆汁酸的产生，并允许艰难梭菌孢子萌发和大肠生长。
4. Ursodeoxycholic Acid (Ursodiol) Significantly Alters the Gut Microbiota and Bile Acid Metabolome in Conventional Mice [C] . American College of Veterinary Internal Medicine Forum Conference . 2019

机译：核糖核酸（Ursodiol）在常规小鼠中显着改变肠道微生物酵母和胆汁酸代谢物
5. Association of Stool Bile Acid Profiles with Clostridioides Difficile Infection Treatment Regimens and Related Changes in the Gut Microbiota [D] . ?Qian, Xi 2020

机译：用梭菌偶氮偶胆梭菌感染治疗方案的粪便胆汁酸谱和肠道微生物瘤中的相关变化
6. Ursodeoxycholic Acid (UDCA) Mitigates the Host Inflammatory Response during Clostridioides difficile Infection by Altering Gut Bile Acids [O] . Jenessa A. Winston, Alissa J. Rivera, Jingwei Cai, 2020

机译：通过改变肠胆汁酸性酸纤维酰胺酸纤维纤维素酸纤维酸（UDCA）减轻宿主炎症反应
7. Ursodeoxycholic acid (UDCA) mitigates the host inflammatory response during Clostridioides difficile infection by altering gut bile acids which attenuates NF-κB signaling via bile acid activated receptors [O] . Jenessa A. Winston, Alissa J. Rivera, Jingwei Cai, 2020

机译：通过改变通过胆汁酸活化受体衰减NF-κB信号传导的肠胆汁酸纤维纤维素感染核酸胆酸（UDCA）减轻梭氧钛酰胺差异感染期间的宿主炎症反应

Defining the Dynamics Between the Gut Microbiota, Microbial Derived Secondary Bile Acid Ursodeoxycholic Acid (UDCA), and Clostridioides difficile Pathogenesis

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