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Novel Antimicrobial Development by Targeting the First Two Committed Enzymes in the Methyl Erythritol Phosphate Pathway, DXP Reductoisomerase and MEP Cytidylyltransferase

机译：通过靶向甲基赤藓糖醇磷酸途径，DXP还原异构酶和MEP胞苷转移酶中的前两种已承诺酶来开发新型抗菌药物

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作者
Haymond, Amanda.;
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作者单位

George Mason University.;

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授予单位 George Mason University.;
学科
学位 Ph.D.
年度 2017
页码 324 p.
总页数 324
原文格式 PDF
正文语种 eng
中图分类
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专利

1. Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme. [J] . Singh N, Cheve G, Avery MA, Current pharmaceutical design . 2007,第11期

机译：靶向甲基赤藓糖醇磷酸酯（MEP）途径以发现新型抗疟疾，抗菌和除草药物：抑制1-脱氧-D-木酮糖-5-磷酸还原异构酶（DXR）酶。
2. Targeting the Methyl Erythritol Phosphate (MEP) Pathway for Novel Antimalarial, Antibacterial and Herbicidal Drug Discovery: Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (DXR) Enzyme [J] . Nidhi Singh Gweneal Cheve Mitchell A. Avery Christopher R. McCurdy Current Pharmaceutical Design . 2007,第11期

机译：针对新型抗疟疾，抗细菌和除草剂药物发现的磷酸甲基赤藓糖醇（MEP）途径：抑制1-脱氧-D-木酮糖-5-磷酸还原异构酶（DXR）酶
3. Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway [J] . Carretero-Paulet L, Ahumada I, Cunillera N, Plant physiology . 2002,第4期

机译：编码1-脱氧-D-木酮糖5-磷酸还原异构酶的拟南芥DXR基因的表达和分子分析，2-C-甲基-D-赤藓糖醇4-磷酸途径的第一个固定酶
4. Molecular Cloning, Characterization and Functional Analysis of the Genes Encoding DXR and DXS, the Two Enzymes in the MEP Pathway, from Amomum villosum Lour. [C] . Yang Jinfen, Adhikari Megha Nath, Liu Hui, Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：砂仁砂仁编码MEP途径中的两种酶DXR和DXS的基因的分子克隆，表征和功能分析。
5. Development of Chromatography and Mass Spectrometry Methods for Enzyme Kinetics and Inhibition in Glycolysis and the Methylerythritol Phosphate (MEP) Pathways [D] . Carr, Allison Fabino 2019

机译：糖酵解和甲基赤藓糖醇磷酸（MEP）途径中酶动力学和抑制作用的色谱和质谱方法的发展
6. Expression and Molecular Analysis of the Arabidopsis DXR Gene Encoding 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase the First Committed Enzyme of the 2-C-Methyl-d-Erythritol 4-Phosphate Pathway [O] . Lorenzo Carretero-Paulet, Iván Ahumada, Nuria Cunillera, 2002

机译：编码1-脱氧-d-木酮糖5-磷酸还原异构酶2-C-甲基-d-赤藓糖醇4-磷酸途径的第一个酶的拟南芥DXR基因的表达与分子分析
7. Expression and Molecular Analysis of the Arabidopsis DXR Gene Encoding 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase, the First Committed Enzyme of the 2-C-Methyl-d-Erythritol 4-Phosphate Pathway1 [O] . Carretero-Paulet, Lorenzo, Ahumada, Iván, Cunillera, Nuria, 2002

机译：编码1-脱氧-d-木酮糖5-磷酸还原异构酶，2-C-甲基-d-赤藓糖醇4-磷酸途径的第一个酶的拟南芥DXR基因的表达与分子分析

Novel Antimicrobial Development by Targeting the First Two Committed Enzymes in the Methyl Erythritol Phosphate Pathway, DXP Reductoisomerase and MEP Cytidylyltransferase

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