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Nucleic acid-based TLR agonists for the prevention of genital HSV-2 disease

机译：基于核酸的TLR激动剂，用于预防生殖器HSV-2疾病

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作者
Herbst-Kralovetz, Melissa M.;
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作者单位

The University of Texas Medical Branch Graduate School of Biomedical Sciences;

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授予单位 The University of Texas Medical Branch Graduate School of Biomedical Sciences;
学科
学位 Ph.D.
年度 2006
页码 177 p.
总页数 177
原文格式 PDF
正文语种 eng
中图分类
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专利

1. HSV-2 Infection of Human Genital Epithelial Cells Upregulates TLR9 Expression Through the SP1/JNK Signaling Pathway [J] . Kai Hu, Ming Fu, Jun Wang, Frontiers in Immunology . 2020,第1期

机译：HSV-2人生殖器上皮细胞的感染通过SP1 / JNK信号通路上调TLR9表达
2. Intradermal immunisation using the TLR3-ligand Poly (I:C) as adjuvant induces mucosal antibody responses and protects against genital HSV-2 infection [J] . Emilie Bardel, Remi Doucet-Ladeveze, Cyrille Mathieu, NPJ vaccines. . 2016,第6期

机译：使用TLR3-配体Poly（I：C）作为佐剂的皮内免疫可诱导粘膜抗体反应并防止生殖器HSV-2感染
3. A critical role for IL-15 in TLR-mediated innate antiviral immunity against genital HSV-2 infection. [J] . Thatte A, DeWitte Orr SJ, Lichty B, Immunology and Cell Biology . 2011,第6期

机译：IL-15在TLR介导的针对生殖器HSV-2感染的先天抗病毒免疫中的关键作用。
4. Real-Time Imaging of Bone Marrow Granulocyte Mobilization in Response to TLR Agonists Demonstrates a Necessity for Stromal TLR4 [C] . J.T. Myers, J.C. Griewe, N. Rivera, International Metallographic Society Annual meeting;Microscopy Society of America Annual Meeting;Microanalysis Society Annual meeting . 2011

机译：响应TLR激动剂的骨髓粒细胞动员的实时成像表明基质TLR4的必要性。
5. Effect of oral and gel tenofovir on genital HSV-2 shedding in immunocompetent women. [D] . Bender Ignacio, Rachel A. 2014

机译：口服和凝胶替诺福韦对具有免疫功能的女性生殖器HSV-2脱落的影响。
6. Vaginal Memory T Cells Induced by Intranasal Vaccination Are Critical for Protective T Cell Recruitment and Prevention of Genital HSV-2 Disease [O] . Ayuko Sato, Aldina Suwanto, Manami Okabe, 2014

机译：鼻内接种疫苗诱导的阴道记忆T细胞对于保护性T细胞募集和预防生殖器HSV-2疾病至关重要
7. TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity [O] . Teresa R. Johnson, Srinivas Rao, Robert A. Seder, 2009

机译：TLR9激动剂，但不是TLR7 / 8，用作辅助染色疫苗增强疾病的佐剂，而在原发性RSV感染期间使用作为治疗的激动剂增加疾病严重程度

Nucleic acid-based TLR agonists for the prevention of genital HSV-2 disease

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