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Design, synthesis and mechanistic studies of small molecule inhibitors of the hypoxia inducible factor pathway

机译：低氧诱导因子途径的小分子抑制剂的设计，合成和机理研究

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作者
Mooring, Suazette Reid;
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作者单位

Georgia State University;

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授予单位 Georgia State University;
学科
学位 Ph.D.
年度 2010
页码 91 p.
总页数 91
原文格式 PDF
正文语种 eng
中图分类
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专利

1. Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway [J] . Mooring S.R., Jin H., Devi N.S., Journal of Medicinal Chemistry . 2011,第24期

机译：新型缺氧诱导因子途径小分子抑制剂的设计与合成
2. Design and in vitro activities of N -alkyl- N -[(8- R -2,2-dimethyl-2 H -chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents [J] . Mun J., Jabbar A.A., Devi N.S., Journal of Medicinal Chemistry . 2012,第15期

机译：N-烷基-N-[（8-R -2,2-二甲基-2 H-铬原子-6-基）甲基]杂芳基磺酰胺，新型小分子缺氧诱导因子-1途径抑制剂和药物的设计和体外活性抗癌药
3. Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility [J] . Jalisa H. Ferguson, Zeus De Los Santos, Saroja N. Devi, Journal of enzyme inhibition and medicinal chemistry. . 2017,第1期

机译：具有改善的水溶性的基于苯并吡喃的低氧诱导因子-1途径抑制剂的设计与合成
4. Therapeutic Silencing of Hypoxia-Inducible Factor-1α Using Mixed Micelle Particles Inhibits Prostate Cancer Cell Growth under Hypoxia [C] . Xi-Qiu Liu, Meng-Hua Xiong, Jun Wang World biomaterials congress . 2012

机译：混合胶束粒子对缺氧诱导因子-1α的治疗沉默抑制缺氧条件下前列腺癌细胞的生长
5. Design of novel cancer therapeutics through the validation of PARG as a therapeutic target and the evaluation of small molecule inhibitors of hypoxia-induced transcription. [D] . Block, Katherine Michelle. 2010

机译：通过验证PARG作为治疗靶标并评估低氧诱导的转录的小分子抑制剂来设计新型癌症治疗剂。
6. Design and Synthesis of Novel Small-molecule Inhibitors of the Hypoxia Inducible Factor Pathway [O] . Suazette Reid Mooring, Hui Jin, Narra S. Devi, -1

机译：缺氧诱导因子途径新型小分子抑制剂的设计与合成
7. Design and Synthesis of Novel Small-Molecule Inhibitors of the Hypoxia Inducible Factor Pathway [O] . Suazette Reid Mooring, Hui Jin, Narra S. Devi, 2011

机译：缺氧诱导因子途径新型小分子抑制剂的设计与合成

Design, synthesis and mechanistic studies of small molecule inhibitors of the hypoxia inducible factor pathway

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