There is little data regarding drinking water contaminated with antibiotic resistant (AR) bacteria and the potential human health impacts associated with its consumption. The aim of this study was to determine if AR Escherichia coli contaminated private drinking water (PDW) is a reservoir of transmission of AR E. coli into humans. AR E. coli was cultured from 11.7% PDW (n=8788) and 35.6% (n=953) fecal samples. The most prevalent ARs were to tetracycline (78.9%; 64.3%), ampicillin (37.4%; 64.9%) and sulfonamides (46.4%; 56.9%) in PDW and fecal samples, respectively. Multidrug resistance (resistance to more than one antibiotic) was common in water (7.3%; n=8788) and human (27.1%; n=921) samples. Genetically related strains of AR E. coli, as determined by pulsed-field gel electrophoresis, were identified in PDW and fecal isolates of the individuals consuming the contaminated PDW, indicating that PDW may be a vehicle of transmission for AR E. coli into the human population.
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机译：很少有关于饮用水被抗生素抗性（AR）细菌污染以及与饮用水相关的潜在人类健康影响的数据。这项研究的目的是确定受AR大肠杆菌污染的私人饮用水（PDW）是否是AR大肠杆菌向人类传播的蓄水池。从11.7％PDW（n = 8788）和35.6％（n = 953）粪便样品中培养AR大肠杆菌。在PDW和粪便样本中，最常见的AR分别是四环素（78.9％; 64.3％），氨苄青霉素（37.4％; 64.9％）和磺酰胺（46.4％; 56.9％）。在水（7.3％； n = 8788）和人（27.1％； n = 921）样品中，多药耐药性（对一种以上抗生素的耐药性）很常见。如通过脉冲场凝胶电泳确定的，在食用受污染PDW的个体的PDW和粪便分离物中鉴定出与AR大肠杆菌的遗传相关菌株，这表明PDW可能是AR大肠杆菌向人类传播的媒介。人口。
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