Synthesis and Reactivity of N-Heterocyclic Chalcogenone Complexes of Copper and Silver

摘要

This presentation outlines the synthesis and characterization of several unusual two-coordinate copper(I) and silver(I) complexes supported by bulky N-heterocyclic thione (NHT) and selone (NHSe) ligands. More specifically, copper(I) complexes of the general formula (IArE)CuX (E = S, Se; Ar = Xy, Mes, Dipp; X = Cl, Br, I) have been prepared and fully characterized using a variety of spectroscopic and analytical techniques. Similarly, rare examples of homoleptic silver(I) complexes with NHT or NHSe ligands, [Ag(IArE) 2]X (X = NO3, BF4, ClO4, PF6, or SbF6), have also been isolated and fully characterized. The molecular structures of several (IArE)CuX and [Ag(IArE)2]X complexes have been determined by X-ray crystallography, which confirms the monomeric nature for both series of compounds in the solid state. Many of the silver(I) complexes are currently being assessed for potential biological activity against various cancer cell lines.