Effects of bacterial endotoxin on liver mass and hepatocyte volume.

摘要

In this study, a single intraperitoneal injection of E. coli lipopolysaccharide (LPS, 0127:B8) at a sublethal dose (3 mg/kg, LD;Analyses of hepatic dry mass components and hepatic cellular spaces show that only one third of the increase in the total liver mass can be accounted for by the net increase of the dry mass components plus the blood/plasma and/or interstitial fluid in the extrahepatocellular space; and hepatic K