Constituents of marine invertebrates: Chemical and pharmacological properties.

摘要

ixteen compounds belonging to seven distinct classes of organic compounds were isolated from a bryozoan and seven sponges; their structures were characterized by a combination of spectroscopic and chemical methods. The classes of compounds are aliphatic amino alcohols, bromotyrosine-derived peptides, a nucleoside, an alkaloid, sesquiterpenes, bromo and peroxy acids.;The first chemical study of an Hawaiian bryozoan led to isolation of two new amino alcohols 30* and 31. The extract from a Pohnpei sponge, Aplysinella sp., yielded two new bromotyrosine derivatives, psammaplysins D (46) and E (47), which show antiviral and immunosuppressive activities.;ftn*Please refer to dissertation for diagrams.