The effects of insulin and insulin-like growth factor-I on the replication of the human immunodeficiency virus type 1 in vitro.

摘要

nsulin and IGF-I, primarily considered to be metabolic and growth modulatory hormones, were found to inhibit HIV-1 replication in de novo infected CBMC and chronically infected U937 cells in vitro. The effect of IGF-I was seen at physiological concentrations or lower (1.3