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Imaging with diffuse photon density waves.

机译:用散射光子密度波成像。

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摘要

Diffusing photons can be used to probe and characterize optically thick turbid samples such as paints, foams and human tissue. In this work, we present experiments which illustrate the properties of diffuse photon density waves. Our observations demonstrate the manipulation of these waves by adjustment of the photon diffusion coefficients of adjacent media. The waves are imaged, and are shown to obey simple relations such as Snell's Law.; Next we present images of heterogeneous turbid media derived from measurements of diffuse photon density waves. These images are the first experimental reconstructions based on frequency-domain optical tomography. We demonstrate images of both absorbing and scattering homogeneities, and show that this method is sensitive to the optical properties of a heterogeneity. The algorithm employs a differential measurement scheme which reduces the effect of errors resulting from incorrect estimations of the background optical properties.; In addition to imaging absorption and scattering changes, we are also able to image the lifetime and concentration profile of heterogeneous fluorescent media.
机译:漫射光子可用于探测和表征光学上较厚的混浊样品,例如油漆,泡沫和人体组织。在这项工作中,我们提出了说明散射光子密度波特性的实验。我们的观察结果表明,通过调节相邻介质的光子扩散系数可以控制这些波。波被成像,并显示服从简单关系,如斯涅尔定律。接下来,我们从扩散光子密度波的测量结果中得出异质混浊介质的图像。这些图像是基于频域光学层析成像的第一个实验性重建。我们演示了吸收和散射同质性的图像,并表明此方法对异质性的光学性质敏感。该算法采用差分测量方案,该方案减少了由于对背景光学特性的不正确估计而导致的误差影响。除了成像吸收和散射变化外,我们还能够成像异质荧光介质的寿命和浓度分布。

著录项

  • 作者

    O'Leary, Maureen Ann.;

  • 作者单位

    University of Pennsylvania.;

  • 授予单位 University of Pennsylvania.;
  • 学科 Biophysics Medical.; Health Sciences Radiology.
  • 学位 Ph.D.
  • 年度 1996
  • 页码 224 p.
  • 总页数 224
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物物理学;预防医学、卫生学;
  • 关键词

  • 入库时间 2022-08-17 11:49:15

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