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A simulation program for the design of broiler nucleus breeding strategies.

机译:用于设计肉鸡核育种策略的模拟程序。

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摘要

A computer simulation program (BBSIM) was developed that can be used to explore breeding strategies for poultry nucleus populations. The program can create multiple traits with different genetic controls (polygenic, finite locus model, categorical, and mixed inheritance). Several stages in the life of an animal can be defined and traits can be expressed or not expressed at any stage. A dynamic best linear unbiased prediction (BLUP) evaluation that can handle single and multiple trait situations is provided. The coefficient of inbreeding is calculated for each individual. Culling and selection can be based on BLUP estimated breeding value (EBV), an index of EBV, or phenotype. Matings can be random or assortative.; The program was used to study the effect of less stringent convergence criterion (CC) in calculation of EBV on genetic response. The sum of squares of differences between consecutive solutions divided by sum of squares of new solutions was used as the criterion for terminating the iteration process. The average breeding values of the top 2% of individuals increased as the system moved towards the most stringent CC. The gain in average breeding value, however, was very small, beyond a CC of 10{dollar}sp{lcub}-3{rcub}{dollar} and could not justify the extra number of iterations and CPU time that were needed to reach 10{dollar}sp{lcub}-7{rcub}.{dollar}; The program was used to examine the effect of including different amounts of pedigree and historical data on genetic response under single trait BLUP. Using the last two generations of data and pedigree, under a broiler breeding family structure, produced genetic response that was not significantly different from full data and pedigree (10 generations) The amount of CPU time, however, was reduced drastically. The results are of particular importance in studies using simulation.; Whether inbreeding coefficients should be considered or ignored in the construction of A{dollar}sp{lcub}-1{rcub}{dollar} was another question that was addressed using the BBSIM program. With rapid rates of inbreeding, under population structures representative of broiler breeding, pairwise comparisons of average genetic responses found no significant differences in response when inbreeding was accounted for in A{dollar}sp{lcub}-1{rcub}.{dollar}; In a two-trait two-stage selection scheme mimicking selection on body weight and egg number, different culling procedures were applied at stage one. Culling was either on BLUP EBV or phenotype and information of culled animals were either carried forward to the second stage or not carried forward. Culling based on BLUP produced greater response, except when the negative genetic correlation between the two traits was high. When information of the culled individuals was not carried to the next stage, genetic response decreased significantly. It was concluded that there are significant advantages to capturing and utilising information from the first stage selection.
机译:开发了计算机仿真程序(BBSIM),该程序可用于探索家禽核种群的育种策略。该程序可以创建具有不同遗传控制(多基因,有限基因座模型,分类和混合遗传)的多个性状。可以定义动物生命的几个阶段,在任何阶段都可以表达或不表达性状。提供了可以处理单个和多个特征情况的动态最佳线性无偏预测(BLUP)评估。为每个个体计算近交系数。可以基于BLUP估计的育种值(EBV),EBV的指标或表型来进行选育和选择。交配可以是随机的,也可以是随机的。该程序用于研究不太严格的收敛标准(CC)在EBV计算中对遗传反应的影响。连续解之间的差平方和除以新解的平方和被用作终止迭代过程的标准。随着系统向最严格的CC迈进,前2%的个体的平均育种值增加。但是,平均育种值的收益非常小,超过了10 {dollar} sp {lcub} -3 {rcub} {dollar}的CC,无法证明需要额外的迭代次数和CPU时间10 {dollar} sp {lcub} -7 {rcub}。{dollar};该程序用于检查在单一性状BLUP下包括不同数量的谱系和历史数据对遗传反应的影响。使用最近两代的数据和家谱,在肉鸡育种家族结构下,产生的遗传反应与完整的数据和家谱(10代)没有显着差异。但是,CPU时间大大减少了。结果在使用模拟的研究中特别重要。在A {dollar} sp {lcub} -1 {rcub} {dollar}的构造中应考虑还是应忽略近交系数是使用BBSIM程序解决的另一个问题。在近亲繁殖速度快的情况下,在代表肉鸡育种的种群结构下,当在A {dollar} sp {lcub} -1 {rcub}中考虑到近亲繁殖时,平均遗传反应的成对比较发现在反应上没有显着差异。在模仿体重和卵数选择的两特征两阶段选择方案中,在第一阶段采用了不同的剔除程序。剔除是针对BLUP EBV还是表型,并且将被剔除动物的信息转入第二阶段或不转入第二阶段。除了两个性状之间的负遗传相关性很高时,基于BLUP的剔除产生了更大的响应。当不将被剔除者的信息传递到下一阶段时,遗传反应显着下降。结论是,从第一阶段的选择中获取和利用信息具有显着的优势。

著录项

  • 作者

    Mehrabani-Yeganeh, Hassan.;

  • 作者单位

    University of Guelph (Canada).;

  • 授予单位 University of Guelph (Canada).;
  • 学科 Biology Genetics.; Agriculture Animal Culture and Nutrition.
  • 学位 Ph.D.
  • 年度 1997
  • 页码 159 p.
  • 总页数 159
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 遗传学;饲料;
  • 关键词

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