首页> 外文学位 >Overcoming Melanoma Immune Tolerance: Non-specific CTLA-4 Blockade/Interferon-alpha and Antigen Specific Immunization with TLR-9 Stimulation/Local GM-CSF as Components of a Melanoma Immunotherapeutic Strategy and Associated Biomarkers of Therapeutic Benefit.

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Overcoming Melanoma Immune Tolerance: Non-specific CTLA-4 Blockade/Interferon-alpha and Antigen Specific Immunization with TLR-9 Stimulation/Local GM-CSF as Components of a Melanoma Immunotherapeutic Strategy and Associated Biomarkers of Therapeutic Benefit.

机译：克服黑色素瘤的免疫耐受性：非特异性CTLA-4阻断/干扰素-α和抗原特异性免疫，TLR-9刺激/局部GM-CSF作为黑色素瘤免疫治疗策略的组成部分和相关的治疗有益生物标志物。

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作者
Tarhini, Ahmad A.;
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作者单位

University of Pittsburgh.;

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授予单位 University of Pittsburgh.;
学科 Oncology.;Health sciences.;Immunology.
学位 Ph.D.
年度 2011
页码 97 p.
总页数 97
原文格式 PDF
正文语种 eng
中图分类
关键词
入库时间 2022-08-17 11:44:41

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1. Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation [J] . Andrea van Elsas, Arthur A. Hurwitz, James P. Allison The Journal of Experomental Medicine . 1999,第3期

机译：使用抗细胞毒性T淋巴细胞相关抗原4（Ctla-4）和产生粒细胞/巨噬细胞集落刺激因子（Gm-Csf）的疫苗联合免疫治疗B16黑色素瘤，可引起皮下和转移性肿瘤伴有自身免疫性色素沉着的排斥反应
2. Cytotoxic T Lymphocyte Antigen-4 Blockade Enhances Antitumor Immunity by Stimulating Melanoma-Specific T-cell Motility [J] . Tsvetelina Pentcheva-Hoang, Tyler R. Simpson, Welby Montalvo-Ortiz, Cancer immunity . 2014,第10期

机译：细胞毒性T淋巴细胞抗原4阻断通过刺激黑素瘤特定的T细胞运动增强抗肿瘤免疫力。
3. CTLA-4 blockade increases antigen-specific CD8 + T cells in prevaccinated patients with melanoma: Three cases [J] . YuanJ., GinsbergB., PageD., Cancer immunology, immunotherapy : . 2011,第8期

机译：CTLA-4阻断可增加预接种黑素瘤患者的抗原特异性CD8 + T细胞：3例
4. Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation [O] . Andrea van Elsas, Arthur A. Hurwitz, James P. Allison 1999

机译：使用抗细胞毒性T淋巴细胞相关抗原4（Ctla-4）和产生粒细胞/巨噬细胞集落刺激因子（Gm-Csf）的疫苗联合免疫治疗B16黑色素瘤可诱导皮下和转移性肿瘤伴有自身免疫性色素沉着
5. Overcoming Melanoma Immune Tolerance: Non-specific CTLA-4 Blockade/Interferon-alfa and Antigen Specific Immunization with TLR-9 Stimulation/Local GM-CSF as Components of a Melanoma Immunotherapeutic Strategy and Associated Biomarkers of Therapeutic Benefit [O] . Tarhini Ahmad Ali 2011

机译：克服黑素瘤的免疫耐受性：非特异性CTLA-4阻断/干扰素-α和TLR-9刺激/局部GM-CSF的抗原特异性免疫作为黑素瘤免疫治疗策略和治疗益处的相关生物标志物的组成部分

Overcoming Melanoma Immune Tolerance: Non-specific CTLA-4 Blockade/Interferon-alpha and Antigen Specific Immunization with TLR-9 Stimulation/Local GM-CSF as Components of a Melanoma Immunotherapeutic Strategy and Associated Biomarkers of Therapeutic Benefit.

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