Novel rehabilitation protocols after ACL reconstruction suggest early mobilization and loading as soon as possible. So as to realize these scopes the graft and its fixation has to be strong enough right after surgery.; In this study the biomechanical and histological properties of the femoral press-fit fixation were examined. In an excessive study, also in domestic and international respect, the biomechanics and tissue incorporation were examined in a porcine model.; The biomechanical and histological examinations proving graft-incorporation on cadavers and animal models known in the international literature were synthesized in accordance with the aims of this work.; It was proved that the tensile strength and stiffness of the press-fit fixation did not differ significantly from those of the nowadays widely accepted and used interference screw fixation.; The results of the biomechanical experiments were confirmed by the histological examination of the bone block incorporation in the early postoperative period in the animal model.; In a short-term follow-up study it was proved that the press-fit fixation did not differ from the interference screw fixation either in the clinical results.; On the basis of this knowledge it became possible to safely apply the accelerated and effective rehabilitation protocol also in the case of the advantageous press-fit fixation.; This way the rehabilitation after ACL reconstruction and requirements of rapid return to sport or work can be realized in accordance with modern, state of the art guidelines.; All of these experiments served the aim of widespreading, acceptance and safe usage of the advantageous and economically friendly femoral press-fit fixation in Hungary and abroad.
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