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Use of Direct Reading Surface Sampling Methods for Site Characterization and Remediation of Methamphetamine Contaminated Properties

机译:使用直接读取的表面采样方法进行甲基苯丙胺污染特性的现场表征和修复

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摘要

Residual methamphetamine contamination in Clandestine laboratories represents a hazard to emergency response personnel, remediation workers and the general public. To address this threat, two rapid, sensitive surface sampling techniques to assess the location and level of methamphetamine contamination were developed. Both methods employ established industrial hygiene surface sampling materials (wipes and swabs) but differ in their sensitivity and detection technology. One method, based on colorimetric disclosure, detects and confirms a collected sample or visible residues. The second method uses a lateral flow immunochemical assay (LFIA) for semi-quantitative detection of trace contamination. The National Institute for Occupational Safety and Health (NIOSH) partnered with public health agencies to develop applications of the methods for assessment of methamphetamine contamination of suspected properties. These applications focused on safe strategies for site assessment, hazard characterization, and remediation effectiveness. To conduct the field studies, NIOSH researchers and their partners visited more than a dozen suspected laboratories including mobile labs, abandoned properties, occupied residences, and motel rooms. NIOSH found greater than 95% agreement between positive identification of the presence of methamphetamine by LFIA and laboratory-based, liquid chromatography mass spectroscopy (LC-MS) methods. Test results were used to develop site assessments and make personal protective equipment recommendations. Results were also used to conduct process-based decontamination of properties and to make health-based decisions on remediation, re-occupancy of residences, as well as determine the degree of contamination of personal property in an inactive clandestine laboratory. By partnering with stakeholders, NIOSH was able to achieve two primary goals: (1) to develop a level of awareness in health department sanitarians, law enforcement personnel and other first responders that methamphetamine surface contamination was a potentially significant route of exposure; (2) to validate our methods in the field and to develop protocols for proper use and interpretation of the results.
机译:秘密实验室中残留的甲基苯丙胺污染对应急人员,补救工作人员和一般公众构成危害。为了解决这一威胁,开发了两种快速,灵敏的表面采样技术来评估甲基苯丙胺污染的位置和水平。两种方法均使用成熟的工业卫生表面采样材料(擦拭和拭子),但其灵敏度和检测技术不同。一种基于比色法的方法可以检测并确认收集到的样品或可见残留物。第二种方法使用侧流免疫化学分析(LFIA)进行痕量污染的半定量检测。美国国家职业安全与健康研究所(NIOSH)与公共卫生机构合作开发了用于评估甲基苯丙胺可疑财产污染的方法的应用。这些应用程序侧重于用于现场评估,危害特征描述和补救有效性的安全策略。为了进行实地研究,NIOSH的研究人员及其合作伙伴访问了十多个可疑实验室,包括移动实验室,废弃房屋,居住住宅和汽车旅馆。 NIOSH发现,通过LFIA对甲基苯丙胺的存在进行阳性鉴定与基于实验室的液相色谱质谱法(LC-MS)之间存在95%以上的一致性。测试结果用于进行现场评估并提出个人防护设备建议。结果还用于进行基于过程的财产净化,并基于健康的决定进行补救,重新居住,以及在不活跃的秘密实验室中确定个人财产的污染程度。通过与利益相关者合作,NIOSH能够实现两个主要目标:(1)提高卫生部门卫生人员,执法人员和其他第一反应者对甲基苯丙胺表面污染可能是潜在的重要暴露途径的认识; (2)验证我们在现场的方法,并开发协议以正确使用和解释结果。

著录项

  • 来源
    《Surface and dermal sampling》|2010年|p.297-312|共16页
  • 会议地点 San Antonio TX(US)
  • 作者单位

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Denver Federal Center, P.O. Box 25226, Denver, CO 80225-0226;

    Hamilton County Public Health, Environmental Health Division, 250 William Howard Taft, Cincinnati, OH 45219;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH 45226-1998;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 工程材料一般性问题;
  • 关键词

    clandestine lab; methamphetamine; surface wipe; real-time; direct reading;

    机译:秘密实验室甲基苯丙胺表面擦拭;即时的;直接阅读;

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