Evaluation of photodamage with polarization-sensitive optical coherence tomography

摘要

Polarization sensitive optical coherence tomography (PS-OCT) is an extension of conventional optical coherence tomography (OCT) which enable the function to investigate birefringence characteristic of materials of biological tissue. In this research, we utilized PS-OCT for evaluation of photodamage on skin and several parameters were developed to investigate the photodamage including birefringence, diattenuation and depolarization properties of mouse skin. Additionally, the recovering progress of mouse skin was observed. The results indicate that the birefringence of skin is changed by laser irradiation.