A portable optical fiber probe for in vivo brain temperature measurements

摘要

We report on the development of an optical fiber based probe for in vivo measurements of brain temperature. By using a thin layer of rare-earth doped tellurite glass on the tip of a silica optical fiber a durable probe, suitable for long-term in vivo measurements of temperature can be fabricated. The probe can be interrogated using a portable optical measurement setup, allowing for measurements to be performed outside of standard optical laboratories as no alignment of components is required. This setup is deployed to a medical research laboratory to show preliminary results on the use of these optical fibers for in vivo pre-clinical measurements of brain temperature.