Insect Neuropeptide Allatostatins Mimetics:A New Approach to Insect Growth Regulators?

摘要

@@ Insect neuropeptides play a very important role in an insect' s life. The cockroach allatostatins (ASTs) are a family of neuropeptides originally isolated from the cockroach, Diploptera punctata^. Owing to their capacity of inhibiting the production of juvenile hormone by the corpora allata (CA)，ASTs are considered as a potential candidate of Insect Growth Regulators (IGRs). But some disadvantages including rapid degradation by peptidases and poor penetration through insect cuticle preclude their