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Phase contrast mammography with synchrotron radiation: physical aspects of the clinical trial

机译:具有同步加速器辐射的相衬乳房X线照片:临床试验的物理方面

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Purpose: The first clinical facility for synchrotron radiation (SR) mammography is now operative at the SYRMEP beamline of ELETTRA, the SR facility in Trieste, Italy. The mammographic facility and the preliminary results of the clinical trial are presented in this contribution. Method and Materials: The distance between the SR source and the patient is about 30 m; the main features of the X-ray beam are: monochromaticity at ~0.2% bandwith in the energy range 8-35 keV, photon flux of about 10~8 ph/(mm~2 s) and dimensions of 21 cm × 3.5 mm at the compressed breast. An innovative dosimetric system allows the on-line dose control during the examination. The images are acquired by scanning the patient, in prone position, in front of the stationary laminar beam; the average scanning time is about 10 s. The detector is a screen film system; it is at ~2 m from the breast in order to fulfil the so-called Phase Contrast (PhC) requirements. The breast thickness and glandularity defines the optimal beam energy for each examination. The patients are enrolled by radiologists, after routine examinations, on the basis of BI-RADS classification, according the research program approved by the local Ethical Committee. Results: This communication concerns the first 9 patients underwent the SR PhC mammography; the images match the quality obtained in previous in vitro studies. With reference to conventional mammography the diagnostic quality of the radiological images is better, without increasing the delivered dose to the patient.
机译:目的:第一个同步辐射X线乳房摄影术的临床设施现已在位于意大利的里雅斯特的SR设施ELETTRA的SYRMEP射线线上运行。乳房X线照相设备和临床试验的初步结果在此文稿中介绍。方法和材料:SR源与患者之间的距离约为30 m; X射线束的主要特征是:在能量范围为8-35 keV时在〜0.2%带宽处具有单色性,光子通量约为10〜8 ph /(mm〜2 s),并且在21°C时尺寸为21 cm×3.5 mm乳房受压。创新的剂量系统可在检查过程中进行在线剂量控制。图像是通过俯卧在固定层流束前方扫描患者而获得的;平均扫描时间约为10 s。检测器是屏幕胶片系统;它距离乳房约2 m,以满足所谓的相衬(PhC)要求。乳房的厚度和腺体定义了每次检查的最佳束能量。根据当地伦理委员会批准的研究计划,在常规检查后,根据BI-RADS分类,由放射科医生对患者进行登记。结果:该交流涉及前9例行SR PhC乳腺X线摄影的患者;图像与以前的体外研究获得的质量相符。参照常规的乳房X线照相术,放射线图像的诊断质量更好,而没有增加向患者的递送剂量。

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