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The variability of software scoring of the CDMAM phantom associated with a limited number of images

机译:与有限数量的图像相关联的CDMAM体模的软件评分可变性

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Software scoring approaches provide an attractive alternative to human evaluation of CDMAM images from digital mammography systems, particularly for annual quality control testing as recommended by the European Protocol for the Quality Control of the Physical and Technical Aspects of Mammography Screening (EPQCM). Methods for correlating CDCOM-based results with human observer performance have been proposed. A common feature of all methods is the use of a small number (at most eight) of CDMAM images to evaluate the system. This study focuses on the potential variability in the estimated system performance that is associated with these methods. Sets of 36 CDMAM images were acquired under carefully controlled conditions from three different digital mammography systems. The threshold visibility thickness (TVT) for each disk diameter was determined using previously reported post-analysis methods from the CDCOM scorings for a randomly selected group of eight images for one measurement trial. This random selection process was repeated 3000 times to estimate the variability in the resulting TVT values for each disk diameter. The results from using different post-analysis methods, different random selection strategies and different digital systems were compared. Additional variability of the 0.1 mm disk diameter was explored by comparing the results from two different image data sets acquired under the same conditions from the same system. The magnitude and the type of error estimated for experimental data was explained through modeling. The modeled results also suggest a limitation in the current phantom design for the 0.1 mm diameter disks. Through modeling, it was also found that, because of the binomial statistic nature of the CDMAM test, the true variability of the test could be underestimated by the commonly used method of random re-sampling.
机译:软件评分方法提供了一种有吸引力的替代方法,可以替代人工评估数字化乳腺X射线摄影系统中的CDMAM图像,特别是按《欧洲乳腺X射线摄影筛查技术和物理控制质量协议》(EPQCM)推荐的年度质量控制测试。已经提出了将基于CDCOM的结果与人类观察者表现相关的方法。所有方法的共同特征是使用少量(最多八个)CDMAM图像来评估系统。这项研究的重点是与这些方法相关的估计系统性能的潜在可变性。在精心控制的条件下,从三个不同的数字乳腺X线摄影系统中获取了36组CDMAM图像。每个圆盘直径的阈值可见度厚度(TVT)是使用先前报告的分析后方法从CDCOM评分中随机确定的一组八幅图像的CDCOM评分确定的,以进行一次测量试验。重复此随机选择过程3000次,以估计每个圆盘直径的结果TVT值的可变性。比较了使用不同的后分析方法,不同的随机选择策略和不同的数字系统得到的结果。通过比较在相同条件下从同一系统获取的两个不同图像数据集的结果,探索了0.1 mm圆盘直径的其他可变性。通过建模解释了实验数据估计的误差的大小和类型。建模结果还表明,对于直径为0.1 mm的磁盘,当前的幻像设计存在局限性。通过建模,还发现由于CDMAM测试的二项式统计性质,使用常用的随机重采样方法可能会低估测试的真实变异性。

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