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Spectroscopy in pharmaceutical development: an overview

机译:药物开发中的光谱学:概述

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Abstract: Spectroscopic techniques play a key role in the everyday work of the pharmaceutical analyst. In addition to the normal use of the various spectroscopies for simple, routine analyses, a pharmaceutical analytical chemist might use spectroscopy to perform a host of additional functions. These might include, for example, the characterization of a polymorphic substance by either X-ray diffraction or nuclear magnetic resonance spectroscopy, the identification of a foreign material in a tablet dosage form by infrared microspectroscopy, or the selection of a wavelength for liquid chromatographic analysis by photodiode array ultraviolet-visible spectroscopy. The following presentation is meant to acquaint the non-pharmaceutical chemist with some of the ways spectroscopy is utilized in the pharmaceutical analysis research and development laboratory.!0
机译:摘要:光谱技术在药物分析师的日常工作中起着关键作用。除了正常使用各种光谱仪进行简单的常规分析外,药物分析化学家还可以使用光谱仪执行许多附加功能。这些可能包括,例如,通过X射线衍射或核磁共振波谱表征多态性物质,通过红外光谱法鉴定片剂剂型中的异物,或选择液相色谱分析的波长通过光电二极管阵列紫外可见光谱。以下演示旨在使非药物化学家熟悉在药物分析研究与开发实验室中使用光谱学的一些方法。!0

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