Sustainable Production of Industrial Chemicals Using Microbial Biocatalysts: 1,4-Butanediol

摘要

1. BDO pathway involves 4 reduction steps - redox intensive 2. BDO pathway generates 1 extra NAD(P)H and no excess ATP 3. Balance energy, redox and maintain high NAD(P)H/NAD(P)~+ ratio 4. Microaerobic production (DO ≈ 0) required for optimal performance.