Effects of Pulse Current on Proliferation Behavior and Activity of Osteoblast-like Cells on Pure Titanium

摘要

Titanium and its alloys are widely used as metallic biomaterial because they exhibit superior mechanical properties, biocompatibility and corrosion resistance. The excellent corrosion resistance of titanium based materials is essentially attributed to passive films. Therefore, structure and properties of passive films have been extensively examined by electrochemical approaches as well as surface analytical techniques. Biological factors such as protein and cells have been reported to affect the corrosion behavior of titanium and titanium alloys. On the other hand, it has been reported that electrochemical reactions occurred on metallic substrates also cause some impacts on cell activities. In the present work, we focus on effects of cathodic reactions on proliferation behavior and activity of osteoblast-like cells on pure titanium.