13 C NMR Spectroscopic Studies of Intra- and Intermolecular Interactions of Amino Acid Derivatives in Solutions

摘要

It is well known that compounds having polar functional groups, such as a carbonyl group and a hydroxyl group, can form aggregates by inter- or intramolecular forces such as hydrogen bonding and dipolar-dipolar interaction in a solution. For measurement of such forces, we recently reported that the chemical shifts of the carbonyl carbons in 13 C NMR have good correlation with an empirical parameter for solvent polarities, ET N , depending on the structures.