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Diffusion Tensor Imaging and Its Potential Applications in Clinical Neurology

机译:扩散张量成像及其在临床神经病学中的潜在应用

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Magnetic resonance imaging (MRI) is the cornerstone of neurological diagnosis in the veterinary clinical setting. As a mainstay, clinical MRI involves the use of standard structural sequences. These sequences provide vital information on structural and intensity brain changes that occur secondary to neurological disease which help to refine differential diagnoses and direct clinical decision making. There is, however, a limitation to the amount of information that can be deduced from these standard sequences, with definitive diagnoses rarely possible and several disease processes, such as epilepsy and degenerative myelopathy, that they are insensitive at detecting. These limitations are well recognised in the wider field of neuroimaging research and have resulted in the development of multiple advanced neuroimaging techniques that are more sensitive to neuropathology and provide more information towards the functional abnormalities present. Once such technique is diffusion tensor imaging (DTI).
机译:磁共振成像(MRI)是兽医临床环境中神经诊断的基石。作为一个主要的,临床MRI涉及使用标准结构序列。这些序列提供了关于结构和强度脑变化的重要信息,其发生的神经疾病是有助于细化鉴别诊断和直接临床决策。然而,存在可以从这些标准序列推导的信息量的限制很少诊断,很少有可能,并且几种疾病方法,例如癫痫和退行性髓病,它们在检测中不敏感。这些限制在神经影像学研究的更广泛的领域中得到了很好的认可,并导致发育多种先进的神经影像学技术对神经病理学更敏感,并提供更多信息朝着存在的功能异常。一旦这样的技术是扩散张量成像(DTI)。

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