IDEAS: An online tool to Identify Differential Expression of genes for Applications in genome-wide Studies

摘要

We developed an online tool called IDEAS to Identify Differential Expression of genes for Applications in genome-wide Studies. We used The Cancer Genome Atlas (TCGA) date to demonstrate the effectiveness and user friendly interface called GeneExpressor of this tool. In particular, cancer is a disease that is not only complex, in that many genetic variations contribute to malignant transformation, but also wildly heterogeneous, in that genetic mechanisms can vary significantly between patients. Early diagnosis and effective treatment of cancer have been always remained challenging.