Research on the Clinical Trials for Group Sequential Design of α Consumption Function Based on Condition Test for Efficiency

摘要

It takes the group sequential design as a method during the period of having interim analysis, in the clinical trial period, it can have multiple statistical analysis, which also can make an early decision to stop testing, so as to save manpower, material and financial resources and so on. In this paper, it takes the definition of group sequential design as the starting point, with the help of the interpretation of the effectiveness of group sequential testing theory, making analysis on the application of α consumption function as the method in clinical trials.