Fabrication of Supramolecular Structured Hydrogels Based on Diels-Alder Click Reaction

摘要

A novel kind of supramolecular structrued hydrogels were fabricated by Diels-Alder click reaction between furan-functionalized polypseudorotaxanes and polymeric dienophiles. Firstly, polypseudorotaxanes were prepared by supramolecular self-assembly of furan-terminated poly(ethylene glycol)(PEG) and α-cyclodextrins (CDs) in water. And polymeric dienophiles were synthesized by a coupling reaction between copolymer of hydroxyethyl methacrylate and N, N-dimethyl acrylamide and N-maleoyl alanine (AMI). The supramolecular structured hydrogels were prepared by Diels-Alder reaction in water.