Ultraviolet-based photoacoustic microscopy (UV-PAM) has recently been demonstrated as a promising tool to overcomethe time-consuming sample preparation procedure in traditional pathological analysis. In order to achieve high-speed UVPAMfor clinical usage, we implemented UV-PAM with a single-axis galvo mirror scanner. With our UV laser operatingat a repetition rate of 55 kHz, our system produced images ~5.5 times faster than the previously reported point-by-pointraster scanning based UV-PAM, with a lateral resolution of ~1.0 μm. Histology-like images of a mouse brain slice wereacquired by our system, showing its potential as an intraoperative imaging tool for surgical margin assessment.
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