4-Substituted Coumarin Antioxidants

摘要

Few derivatives of 3-arylmethyl-4-hydroxycoumarin and 4-aryl-3,4-dihydrocoumarin as potential free radical scavengers were synthesized. The antiradical activity of these compounds was measured according to l,l-diphenyl-2-picrylhidrazyl and galvinoxyl tests. It strongly depends on phenol-type substituent attached to the coumarin skeleton. Nevertheless the chromen-2-one scaffold by itself plays an important role for the antiradical activity.