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Conformational analysis of novel peptide derivatives with cytostatic activity

机译：细胞抑制活性新型肽衍生物的构象分析

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摘要

Yamamarin and its derivatives exhibit cytostatic activity against rat hepatoma (liver cancer) cells. We synthesized several yamamarin derivatives and investigated its activity and conformation.

机译：山雀及其衍生物对大鼠肝癌（肝癌）细胞表现出细胞抑制活性。我们综合了几个山雀衍生物并调查了其活动和构象。

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《Japanese peptide symposium》|2011年||共1页
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作者
Masakatsu Kamiya; Tomoshi Yoshida; Tomoyasu Aizawa;
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原文格式 PDF
正文语种
中图分类肽类;
关键词
insect peptide; cytostatic activity; peptide cyclization;

机译：昆虫肽;细胞抑制活性;肽环化;

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1. Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: Synthesis, H-1 and C-13 NMR conformational studies, and antiviral and cytostatic evaluations [J] . Prekupec S, Makuc D, Plavec J, Journal of Medicinal Chemistry . 2007,第13期

机译：新型C-6氟化无环侧链嘧啶衍生物：合成，H-1和C-13 NMR构象研究以及抗病毒和细胞抑制评估
2. Cyclic peptide analysis of the biologically active loop region in the laminin alpha3 chain LG4 module demonstrates the importance of peptide conformation on biological activity. [J] . Kato-Takagaki K, Suzuki N, Yokoyama F, Biochemistry . 2007,第7期

机译：层粘连蛋白α3链LG4模块中生物活性环区域的循环肽分析证明了肽构象对生物活性的重要性。
3. Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity [J] . Miranda LP, Winters KA, Gegg CV, Journal of Medicinal Chemistry . 2008,第9期

机译：具有血浆稳定性增强和体内活性延长的构象约束胰高血糖素样肽-1衍生物的设计与合成
4. Conformational analysis of novel peptide derivatives with cytostatic activity [C] . Masakatsu Kamiya, Tomoshi Yoshida, Tomoyasu Aizawa Japanese peptide symposium . 2011

机译：细胞抑制活性新型肽衍生物的构象分析
5. Design and analysis of azobenzene-crosslinked peptides and proteins: Photocontrol over conformation and activity [D] . Burns, Darcy Charles 2008

机译：设计和分析偶氮苯交联的肽和蛋白质：对构象和活性的光控制
6. Novel Coumarin Derivatives Containing 124-Triazole 45-Dicyanoimidazole and Purine Moieties: Synthesis and Evaluation of Their Cytostatic Activity [O] . Krešimir Benci, Leo Mandić, Tomislav Suhina, 2012

机译：包含124-三唑45-二氰基咪唑和嘌呤部分的新型香豆素衍生物：合成和细胞抑制活性的评估
7. Sejtadhéziós peptidszármazékok szintézise daganatgátlás céljából = Synthesis of cell adhesion peptide derivatives as potential cytostatic agents [O] . Süli Mihályné Dr. Vargha Helga, Mihala Nikolett 2007

机译：合成细胞粘附肽衍生物作为潜在的细胞抑制剂

Conformational analysis of novel peptide derivatives with cytostatic activity

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