Label-Free MS Identification of Protein and PTM Biomarkers of Metabolic Disorder Associated Cardiovascular Disease in a Mouse Model

摘要

1. Peptide and Protein and OPTM changes are reflective of CVD 1) The HFHS model at 4 months represents 2) Changes observed correlate with other mouse models a young model 3) Changes observed in mouse correlate well in human 4) OPTMs yield both specific and non-specific changes 5) No obvious differences in DETAPAC or EDTA serum collection 6) Information gained from these CVD models