Untargeted Metabolomics Study of the Plant-Pathogenic Fungus Magnaporthe oryzae by GC × GC × QTOFMS

摘要

Consistent with the role of the NUT1 gene as a nitrogen regulator, MDT1 as a carbon regulator, and TPS1 in integrating carbon and nitrogen metabolism, we observed significant changes in both carbonaceous and nitrogenous metabolites known to play roles in pathogenisis, including glycerol, a metabolite important for turgor generation in the appressorium, and cystathionine, strongly misregulated in the mutant strains. Future work could be directed toward determining the role cystathionine pathways during infection.