Intensity of the Inflammatory Response to Carotid Artery Endarterectomy or Stent Implantation

摘要

Vascular interventions are accompanied by the inflammatory process. We compared serum levels of C-reactive protein (CRP) between patients who underwent carotid endarterectomy (CEA) or angioplasty with stenting (CAS). 21 CEA patients and 33 CAS patients were analyzed. Significant increase of CRP was noticed at the first day after the procedure (median: 11,5 mg/dL, compared to baseline: 2,5 mg/dL). More extensive increase was detected at the 3~(rd) day (median: 20.6mg/dL). CEA was associated with a similar time course of postinterventional CRP as after CAS. At the 3rd day a more pronounced CRP increase was noted after CAS (22,5 mg/dL vs. 15,2 mg/dL). Concluding: Vascular injury after carotid CAS or CEA induces a systemic inflammation. The intensity of the inflammatory response to stent implantation seems to be higher than to CEA.