HIGH SPEED SIMULTANEOUS SLO/OCT IMAGING OF THEHUMAN RETINA WITH ADAPTIVE OPTICS

摘要

We present a new adaptive optics (AO) enhanced high speed imaging system that iscapable of recording scanning laser ophthalmoscope (SLO) and optical coherencetomography (OCT) images, simultaneously. A superluminescent diode (SLD) withcentral wavelength at 841nm and a bandwidth of 51nm is used for imaging. The closedloop AO system consists of two deformable mirrors (one bimorph mirror and one MEMSminor) and a Hartmann-Shack wavefront sensor with a frame rate of 16Hz. Using afiber-based Mach Zehnder interferometer provides equal power returning from the eyefor the SLO and OCT channels and a pixel-to-pixel correspondence between bothchannels. The time domain OCT system is based on a fast transverse scanning of thesample and incorporates a resonant scanner operating at –14kHz. The instrumentcurrently records SLO and OCT images consisting of –700x500 pixels at a frame rate of28fps. A quantitative comparison of the human cone mosaic imaged with SLO and OCTat different eccentricities from the fovea is presented.