Nickel-catalyzed Addition of P(O)-H Bond to Propargyl Alcohols: One-Pot Generation of Phosphoroyl Substituted 1,3-Butadienes via in situ Dehydration

摘要

Diphenylphosphine oxide and related P(O)-H compounds react with propargyl alcohols in the presence of a catalytic amount of Ph_2P(O)OH and nickel(O) complex to produce phosphoroyl butadienes through in situ dehydration.Improved yields of the products are obtained when propargyl alcohols having electron-donating substituents are employed as the substrates.