Direct installation of two carbon units (C~1 and C~2) into a carbon-carbon triple bond of arynes via C~1-C~2 bond cleavage offers facile approach to highly functionalized arenes, being hardly available by conventional methods, and thus, would be of great synthetic significance. In this context, Stoltz's and our groups have already disclosed the C-C bond cleavage reaction, wherein the use of active methylene compounds bearing two electron-withdrawing moieties is the key for the reaction to proceed. We report herein a new C-C bond cleavage reaction using fluorene derivatives, that is, acylfluorenylation, which allows aryl-acyl and aryl-fluorenyl bond-forming processes to occur at neighboring positions of an aromatic skeleton all at once.
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