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5-FLUOROURACIL LOADED BLOCK COPOLYMER NANOSPHERES COMPOSED OF METHOXY POLY(ETHYLENE GLYCOL) AND POLY(D,L-LACTIDE) AS NOVEL ANTICANCER DRUG CARRIER

机译：由甲氧基聚（乙二醇）和聚（D，L-丙交酯）组成的5-氟尿嘧啶嵌段共聚物纳米球作为新型抗癌药物载体

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We prepared amphiphilic block copolymer nanospheres composed of methoxy poly(ethylene glycol) (MePEG) and poly(D,L-lactide) (PDLLA) containing 5-fluorouracil (5-FU) as anticancer drug. The copolymer micelles were prepared by dialysis against water. We could obtain drug loading efficiency of 33.8% when the feed weight ratio of 5-FU to copolymer was 0.2:0.8.

机译：我们制备由甲氧基聚（乙二醇）（Mepeg）和含有5-氟尿嘧啶（5-FU）的聚（D，L-丙交酯）（PDLLA）组成的两亲嵌段共聚物纳米球作为抗癌药物。通过透析液对水制备共聚物胶束。当5-FU的共聚物的进料量比为0.2：0.8时，我们可以获得33.8％的药物加载效率。

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《Annual meeting of the Controlled Release Society 》|2002年||共2页
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作者
Jung-Ho Ahn; Chang-Jo Juna; Dong-Guk Yu;
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正文语种
中图分类制药化学工业 ;
关键词
methoxy poly(ethylene glycol); DL-lactide; 5-fluorouracil; nanosphere; dialysis method;

机译：甲氧基聚（乙二醇）;DL-丙交酯;5-氟尿嘧啶;纳米晶体;透析方法;

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1. Taxol-loaded block copolymer nanospheres composed of methoxy poly(ethylene glycol) and poly(epsilon-caprolactone) as novel anticancer drug carriers. [J] . Kim SY, Lee YM Biomaterials . 2001 ,第13期

机译：紫杉醇负载的嵌段共聚物纳米球由甲氧基聚（乙二醇）和聚（ε-己内酯）作为新型抗癌药物载体。
2. Preparation and characterization of biodegradable nanospheres composed of methoxy poly(ethylene glycol) and DL-lactide block copolymer as novel drug carriers [J] . Kim SY., Lee YM., Shin IG. Journal of Controlled Release: Official Journal of the Controlled Release Society . 1998 ,第1a3期

机译：甲氧基聚乙二醇和DL-丙交酯嵌段共聚物作为新型药物载体的可生物降解纳米球的制备与表征
3. DUAL ANTICANCER DRUG LOADED METHOXY POLY (ETHYLENE GLYCOL)-POLY (ε-CAPROLACTONE) BLOCK COPOLYMERIC MICELLES AS NOVEL DRUG CARRIERS [J] . Anjan Kumar Mohanty, Guru Prasad Mohanta International Journal of Pharmacy and Pharmaceutical Sciences . 2014 ,第9期

机译：双抗癌药装载的甲氧基聚（乙烯-乙二醇）-聚（ε-己内酯）嵌段共聚物胶束作为新型药物载体
4. 5-FLUOROURACIL LOADED BLOCK COPOLYMER NANOSPHERES COMPOSED OF METHOXY POLY(ETHYLENE GLYCOL) AND POLY(D,L-LACTIDE) AS NOVEL ANTICANCER DRUG CARRIER [C] . Jung-Ho Ahn, Chang-Jo Juna, Dong-Guk Yu Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：新型抗癌药载体由甲氧基聚乙二醇和聚（D，L-丙交酯）组成的5-氟尿烷嵌段共聚物纳米球
5. Synthesis and Characterization of Silicate Ester Prodrugs and Poly(ethylene glycol)-b-poly(lactic-co-glycolic acid) Block Copolymers for Formulation into Prodrug-Loaded Nanoparticles. [D] . Wohl, Adam Richard. 2012

机译：硅酸酯酯前药和聚（乙二醇）-b-聚（乳酸-共-乙醇酸）嵌段共聚物的合成和表征，用于配制成载有前药的纳米颗粒。
6. Synthesis and Characterization of Star Poly(ε-caprolactone)-b-Poly(ethylene glycol) and Poly(l-lactide)-b-Poly(ethylene glycol) Copolymers: Evaluation as Drug Delivery Carriers [O] . Fei Wang, Tatiana K. Bronich, Alexander V. Kabanov, -1

机译：星形聚（ε-己内酯）-b-聚（乙二醇）和聚（l-丙交酯）-b-聚（乙二醇）共聚物的合成和表征：评价作为药物输送载体
7. Synthesis and Characterization of Star Poly(ε-caprolactone)-b-Poly(ethylene glycol) and Poly(l-lactide)-b-Poly(ethylene glycol) Copolymers: Evaluation as Drug Delivery Carriers [O] . Fei Wang, Tatiana K. Bronich, Alexander V. Kabanov, 2008

机译：星聚（ε-己内酯）-B-聚（乙二醇）和聚（L-丙交酯）-B-聚（乙二醇）共聚物的合成与表征：评价为药物递送载体

5-FLUOROURACIL LOADED BLOCK COPOLYMER NANOSPHERES COMPOSED OF METHOXY POLY(ETHYLENE GLYCOL) AND POLY(D,L-LACTIDE) AS NOVEL ANTICANCER DRUG CARRIER

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