Investigation of phtalocyanine Al photosensitizer and blood interaction

摘要

The investigation of spectroscopical properties of blood which contains photosensitizers irradiated by laser light is the actual problem of photodynamic therapy. The results of physiological blood characteristics and its oxygenation degree alterations for photosensitizers of tetrasulphanated aluminum phthalocyanine obtained from the experiments are presented in this paper. Spectral characteristics were measured with the use of a double ray spectrophotometer equipped by an integrating sphere. The concentration of drug and the dose of laser light for irradiation were chosen in accordance with the therapeutic ones realized during PDT.