Development of A Simultaneous Quantification Method with HPLC Followed by High Resolution Mass Spectrometry for 'Youchousa-koumoku' to be Surveyed by The Ministry of The Environment, Japan

摘要

The aim of this study is to establish a simultaneous analysis method with HPLC followed by Orbitrap MS for screening of "Youchousa-koumoku" by the ministry of the environment, Japan. Results showed 105 out of 149 items could be detected by Orbitrap MS, and 70 of these could be determined by retention time and accurate mass when Orbitrap MS coupled with an InertSustain AQ-C18 column. The new method is expected to greatly improve the survey