Near-infrared Fluorophore-doped Nanoparticles for in vitro and in vivo Bioimaging

摘要

Near-infrared (NIR) imaging technology has been widely used for bioimaging, since it can achieve deep penetration in biological tissues due to less absorption and scattering of NIR light. In our study, we reported the application of a kind of NIR fluorophore-doped nanoparticles for in vitro and in vivo microscopic bioimaging. Cellular imaging without autofluorescence, as well as vascular imaging of the mouse ear was obtained. The results of our experiments demonstrated NIR fluorophore-doped nanoparticles can be utilized as optical probes for high-contrast and deep-tissue functional bioimaging.